The court tried 23 of those people in absentia.
They were charged with inciting violence against security forces and state institutions during anti-government protests in September 2019 in the port city of Suez — a rare show of dissent since President Abdel-Fattah el-Sissi took power in 2014.
The court also sentenced 44 other people, including children, to jail terms ranging from five to 15 years over the same charges.
Prominent businessman sentenced
Among those sentenced to life in prison was Spain-based Egyptian businessman Mohamed Ali.
Ali, a construction contractor and fledgling actor, burst onto Egypt's political scene in 2019 when he posted videos to social media accusing el-Sissi and the military elite of corruption.
The videos, posted from Spain, went viral and sparked a wave of small scale protests in several cities across Egypt.
Egyptian authorities arrested some 4,000 people after the protests, including well-known academics, activists and lawyers. Rights groups estimate Egypt now holds more than 65,000 political prisoners.
In 2013, after el-Sissi was involved in a coup to oust President Mohammed Morsi, Egypt passed a law that effectively banned all protests except those authorized by police.
