Air raid sirens sounded in the Israeli city of Tel Aviv after midnight and again early in the morning on Tuesday, while there were reports of explosions over Jerusalem and missile attacks in other parts of the country, including Herzliya.
Israeli state radio has described a "rain of missiles" from Iran targeting the country.
Later on Tuesday morning, the Israeli military lifted an instruction to the population to remain in shelters, after first issuing warnings of ongoing attacks.
"A short while ago, sirens sounded in several areas across Israel following the identification of missiles launched from Iran toward the State of Israel," the military said in a statement early in the day.
It added that the air force was "operating to intercept and strike where necessary to eliminate the threat."
The Israeli police said in a statement on the Telegram messaging app that "missiles and shrapnel fell in the Tel Aviv area, causing material damage but no injuries."