Hanuma Vihari, Wriddhiman Saha, Mohammad Siraj and Umesh Yadav were the four members of the 15-member squad who missed out from the playing XI.
Indian team management have gone in with five bowlers. Ravichandran Ashwin and Ravindra Jadeja will be the two spinners, while the three-man pace attack will comprise Mohammed Shami, Ishant Sharma and Jasprit Bumrah.
This is only the second time that Jadeja and Ashwin will be playing a Test match together in England since 2014.
Rohit Sharma and Shubman Gill will open the innings, followed by a middle order comprising Cheteshwar Pujara, Virat Kohli, Ajinkya Rahane, and Rishabh Pant.
India playing XI: Virat Kohli (c), Rohit Sharma, Shubman Gill, Cheteshwar Pujara, Ajinkya Rahane, Rishabh Pant (wk), Ravindra Jadeja, Ravichandran Ashwin, Mohammed Shami, Ishant Sharma, Jasprit Bumrah.(UNI)